Psoriasis may present for the first time at progression to AIDS. There are reports of improvement of psoriasis in the setting of immune reconstitution with ART, after initial flares. HIV infection may alter the course of psoriasis in individual patients with some patients having co-existing patterns of psoriasis such as both guttate psoriasis and psoriasis vulgaris. More extensive lesions with Increased presence of acral lesions and inverse psoriasis are more frequent.1 Severe exfoliative erythroderma may also /dermatological-conditions/references/occur. Patients with HIV infection are more likely to have arthritis associated with psoriasis.