The classic lesions of MC consist of dome shaped, ﬂesh-coloured 2-6 mm papules with central umbilication containing either a molluscum body or caseous material. The papules can be pruritic. Molluscum altered by the immunosuppression of HIV is often larger and more numerous; and persistent lesions may occur. MC tends to appear in patients with HIV infection with advanced disease. Most commonly, MC is on the face, neck, genitals, creases and folds or sites of friction e.g. axilla and groin.