Seborrhoeic dermatitis is a very common non-infectious cutaneous presentation of HIV and is observed in 85% of patients with AIDS. In some instances it may be the initial cutaneous manifestation of HIV disease. Although it can present at any CD4 cell count, increased severity and extent of involvement with poorer response to treatment occurs with worsening immunosuppression. Malassezia may have a role in the pathogenesis of this disease. However, fungal overgrowth or a rise in the levels of IgG titers against the yeast in HIV-1-seropositive patients has not been demonstrated.