Psoriasis affects 2-5% of the population with HIV infection compared to a prevalence of 1-2% in the general population.[143][144]  Patients often present with more severe disease. It has been suggested that the immunodysregulation from HIV infection can trigger psoriasis in those genetically predisposed to it.[145]  The presence of the haplotype Cw*0602 seems to be more prevalent among the population with HIV infection with psoriasis.[146]  The Th17 pathway recently discovered to be involved in psoriasis is subject of active research for potential therapeutic targets. [147])