Summary of vaccination recommendations for HIV-infected adults

Table 1: Summary of vaccination recommendations for HIV-infected adults

 

Vaccine

Recommendation

Diphtheria, tetanus, pertussis

According to routine recommendations

Haemophilus influenza type B

According to routine recommendations

Hepatitis A virus

2 doses (0, 6 months) for at risk groups with CD4+ T cells >350/mL

3 doses (0, 1, 6 months) for at risk groups if CD4+ T cells <350/mL

Hepatitis B virus

3 doses (0, 1, and 6 months) 40mg if nonimmune

Check HBsAb 4-8 weeks after last dose, if <10IU, 1x 40mg dose

Human papilloma virus

Females <45 years and males <26 years

3 doses (0, 1, 6 months)

Influenza virus

Annual

Measles, mumps, rubella viruses

1 or 2 doses if CD4+ T cells >200/mL and non-immune

Not recommended if CD4+ T cells <200/mL

Meningococcal ACWY

2 doses

Meningococcal B

2 doses (no clinical data but recommended)

Pneumococcal conjugate 13

1 dose all

Pneumococcal

polysaccharide 23

1 dose at least 12 months after PCV13

Repeat dose 5 years later (2 lifetime doses)

Varicella virus

2 doses if CD4+ T cells >200/mL and IgG antibody negative

Not recommended if CD4+ T cells <200/mL

Herpes zoster virus

Consider use of 1 dose in patients with CD4+ T cells >200-350/mL and VZV IgG antibody seropositive

Not recommended if CD4+ T cells <200/mL