Predictors of HAND

Studies suggest predictors of HAND include: past history of AIDS-defining central nervous system (CNS) disease,[18] other CNS disease,[19] low T cell nadir,[20] longer duration of HIV infection, [21] drug and alcohol use,[22]  and hepatitis C infection.[23]. Additionally, the risk of HAND increases as the CD4+ counts decline below 350cells/uL and with higher plasma viral load. [24]